Prazosin

Prazosin Brands

Brand Name	Manufacturer Name	Distributor	Drug Strength	Packaging	Formulation	Formulation Strength	Price
	Ltd.	Ltd	450mg/50mg	30	Tablet	per tablet	KES
	Ltd	(K) Ltd.	450mg/50mg	30	Tablet	per tablet	KES

Prazosin More info
Drug Indication	Hypertension; congestive heart failure; raynauds syndrome; benign prostatic hyperplasia.
Precautions	First dose may cause collapse due to hypotension (therefore should be taken on retiring to bed); elderly; cataract surgery (risk of intra-operative floppy iris syndrome); may affect performance of skilled tasks e.g. driving.
Contra-Indications	Congestive heart failure due to mechanical obstruction (e.g. aortic stenosis).hepatic impairment; renal impairment; pregnancy; breast-feeding.
Side Effects	Dyspnoea; nervousness; urinary frequency; less commonly insomnia, paraesthesia, sweating, arthralgia, eye disorders, tinnitus, and epistaxis; rarely pancreatitis, flushing, vasculitis, bradycardia, hallucinations, worsening of narcolepsy, gynaecomastia, urinary incontinence, and alopecia.
Dosage	Hypertension, 500mcg 2-3 times daily for 3-7 days, the initial dose on retiring to bed at night (to avoid collapse, see cautions); increased to 1mg 2-3 times daily for a further 3-7 days; further increased if necessary to max. 20mg daily in divided doses. Congestive heart failure 500mcg 2-4 times daily (initial dose at bedtime), increasing to 4mg daily in divided doses; maintenance 4-20mg daily in divided doses (but rarely used). Raynauds syndrome (but efficacy not established, initially 500mcg twice daily (initial dose at bedtime) increased, if necessary, after 3-7 days to usual maintenance 1-2mg twice daily.
Pregnancy Category	Category C
Pregnancy Category Description	Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible
Drug Category	DRUGS ACTI NG ON THE CARDIO-VASCULAR SYSTEM
Drug Sub-Category	Alpha-adrenoceptor blocking agents